Candid Summaries on CBD Studies

Cancer: Enhacing the Efficacy of Cancer Treatment with CBD

KEY TAKEAWAYS:

  • Previous findings report CBD’s ability to inhibit tumor invasion and cancer metastasis
  • 50% of dogs over 10 years of age have cancer and 20% of cats will develop cancer in their lifetime
  • Superior tumor cell killing was achieved with CBD than with 4 Gy (unit of radiation dose) of RT alone
  • Results support a greater effectiveness in killing tumor cells when combining CBD and radiotherapy (RT)
  • CBD use in combination with RT increased the survival rates of the studied mice
  • There is a clear demonstration of a bigger survival rate of CBD-treated mice comparing with the control group (no treatment)
  • In situ (in the exact local) delivery of CBD with smart biomaterials allows bigger concentrations of CBD to reach its target
  • CBD treatment occasioned an 80% survival rate (vs 50% in the control group) in mice with tumors, whereas the use of smart biomaterials loaded with CBD resulted in a 100% survival rates 
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Cancer: Long-Term Safety and Tolerability of Cannabinoids use in Patients with Terminal Cancer-related Pain

KEY TAKEAWAYS:

  • Long-term use of cannabinoids was well tolerated and no loss of effect was perceived
  • Patients on treatment did not seek to increase cannabinoids dose nor did they seek any other treatment for pain relief
  • Quality of life domains of insomnia, fatigue and pain showed an improvement after cannabinoid administration and no harmful effect was observed in the domain of cognitive functioning
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Cancer: Efficacy, Safety & Tolerability of Cannabinoids in Patients with Intractable Cancer-Related Pain

KEY TAKEAWAYS:

  • 43% of participants experienced a  ≥30% reduction in cancer-related pain intensity after cannabinoid treatment 
  • 20% of cats and 25% of dogs will be diagnosed with cancer in their lifetime
  • After 2 weeks of receiving CBD+THC in addition to all other treatments, there was a statistically significant reduction in pain severity when compared with placebo
  • The addition of CBD resulted in a increase of 20% in the response rate 
  • A greater proportion of patients in the cannabinoid treatment group reduced other pain medication doses whereas the highest proportion of increases in dose was in the placebo group
  • Administration of THC+CBD was well tolerated and no safety concerns were identified 
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